DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression

DNA damage commonly occurs in cancer cells as a result of endogenous and tumor microenvironmental stress. In this study, we applied immunohistochemistry to study the expression of phosphorylated Chk2 (pChk2), a surrogate marker of the DNA damage response, in high grade and low grade of ovarian serou...

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Detalles Bibliográficos
Autores principales: Kshirsagar, Malti, Jiang, Wei, Shih, Ie-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199114/
https://www.ncbi.nlm.nih.gov/pubmed/22028712
http://dx.doi.org/10.1155/2012/621685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199114/
https://www.ncbi.nlm.nih.gov/pubmed/22028712
http://dx.doi.org/10.1155/2012/621685

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