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NBM-HD-1: A Novel Histone Deacetylase Inhibitor with Anticancer Activity

HDAC inhibitors (HDACis) have been developed as promising anticancer agents in recent years. In this study, we synthesized and characterized a novel HDACi, termed NBM-HD-1. This agent was derived from the semisynthesis of propolin G, isolated from Taiwanese green propolis (TGP), and was shown to be...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Jan, Liang, Yu-Chih, Chuang, Shuang-En, Chi, Li-Ling, Lee, Chi-Yun, Lin, Chia-Wei, Chen, Ai-Ling, Huang, Jing-Shi, Chiu, Chun-Jung, Lee, Cheng-Feng, Huang, Chung-Yang, Chen, Chia-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199191/
https://www.ncbi.nlm.nih.gov/pubmed/22046195
http://dx.doi.org/10.1155/2012/781417