Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase

BACKGROUND: Cellular clearance of reactive oxygen species is dependent on a network of tightly coupled redox enzymes; this network rapidly adapts to oxidative conditions such as aging, viral entry, or inflammation. Current widespread use of shRNA as a means to perturb specific redox couples may be m...

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Detalles Bibliográficos
Autores principales: Kippner, Linda E, Finn, Nnenna A, Shukla, Shreya, Kemp, Melissa L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199260/
https://www.ncbi.nlm.nih.gov/pubmed/21995976
http://dx.doi.org/10.1186/1752-0509-5-164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199260/
https://www.ncbi.nlm.nih.gov/pubmed/21995976
http://dx.doi.org/10.1186/1752-0509-5-164

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