An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast Dicer

Dicer proteins function in RNA interference (RNAi) pathways by generating small RNAs (sRNAs). Here, we report the solution structure of the C-terminal domain of Schizosaccharomyces pombe Dicer (Dcr1). The structure reveals an unusual double-stranded RNA binding domain (dsRBD) fold embedding a novel...

Descripción completa

Detalles Bibliográficos
Autores principales: Barraud, Pierre, Emmerth, Stephan, Shimada, Yukiko, Hotz, Hans-Rudolf, Allain, Frédéric H-T, Bühler, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199388/
https://www.ncbi.nlm.nih.gov/pubmed/21847092
http://dx.doi.org/10.1038/emboj.2011.300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199388/
https://www.ncbi.nlm.nih.gov/pubmed/21847092
http://dx.doi.org/10.1038/emboj.2011.300

Ejemplares similares