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Human piRNAs Are Under Selection in Africans and Repress Transposable Elements

Piwi-interacting RNAs (piRNAs) are a recently discovered class of 24- to 30-nt noncoding RNAs whose best-understood function is to repress transposable elements (TEs) in animal germ lines. In humans, TE-derived sequences comprise ∼45% of the genome and there are several active TE families, including...

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Detalles Bibliográficos
Autores principales: Lukic, Sergio, Chen, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199439/
https://www.ncbi.nlm.nih.gov/pubmed/21613236
http://dx.doi.org/10.1093/molbev/msr141