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Human piRNAs Are Under Selection in Africans and Repress Transposable Elements
Piwi-interacting RNAs (piRNAs) are a recently discovered class of 24- to 30-nt noncoding RNAs whose best-understood function is to repress transposable elements (TEs) in animal germ lines. In humans, TE-derived sequences comprise ∼45% of the genome and there are several active TE families, including...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199439/ https://www.ncbi.nlm.nih.gov/pubmed/21613236 http://dx.doi.org/10.1093/molbev/msr141 |