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Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species
Tumor recurrence after chemotherapy or radiation remains a major obstacle to successful cancer treatment. A subset of cancer cells, termed cancer stem cells, can elude conventional treatments and eventually regenerate a tumor that is more aggressive. Despite the large number of studies, molecular ev...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199523/ https://www.ncbi.nlm.nih.gov/pubmed/21878644 http://dx.doi.org/10.1074/jbc.M110.200675 |