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Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species

Tumor recurrence after chemotherapy or radiation remains a major obstacle to successful cancer treatment. A subset of cancer cells, termed cancer stem cells, can elude conventional treatments and eventually regenerate a tumor that is more aggressive. Despite the large number of studies, molecular ev...

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Detalles Bibliográficos
Autores principales:	Achuthan, Santhi, Santhoshkumar, Thankayyan R., Prabhakar, Jem, Nair, S. Asha, Pillai, M. Radhakrishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199523/ https://www.ncbi.nlm.nih.gov/pubmed/21878644 http://dx.doi.org/10.1074/jbc.M110.200675

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