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Celecoxib and acetylbritannilactone interact synergistically to suppress breast cancer cell growth via COX-2-dependent and -independent mechanisms

The use of celecoxib is associated with a significant decrease in breast cancer risk. However, the long-term use of high-dose celecoxib might be limited owing to cardiovascular side effects. In this study, we found that acetylbritannilactone (ABL), extract from a Chinese medicinal herb, could reduce...

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Detalles Bibliográficos
Autores principales: Liu, B, Wen, J K, Li, B H, Fang, X M, Wang, J J, Zhang, Y P, Shi, C J, Zhang, D Q, Han, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199716/
https://www.ncbi.nlm.nih.gov/pubmed/21796157
http://dx.doi.org/10.1038/cddis.2011.64