Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters

Development of multidrug resistance (MDR) is a major deterrent in the effective treatment of metastatic cancers by chemotherapy. Even though MDR and cancer invasiveness have been correlated, the molecular basis of this link remains obscure. We show here that treatment with chemotherapeutic drugs inc...

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Detalles Bibliográficos
Autores principales: Saxena, M, Stephens, M A, Pathak, H, Rangarajan, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199722/
https://www.ncbi.nlm.nih.gov/pubmed/21734725
http://dx.doi.org/10.1038/cddis.2011.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199722/
https://www.ncbi.nlm.nih.gov/pubmed/21734725
http://dx.doi.org/10.1038/cddis.2011.61

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