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Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters
Development of multidrug resistance (MDR) is a major deterrent in the effective treatment of metastatic cancers by chemotherapy. Even though MDR and cancer invasiveness have been correlated, the molecular basis of this link remains obscure. We show here that treatment with chemotherapeutic drugs inc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199722/ https://www.ncbi.nlm.nih.gov/pubmed/21734725 http://dx.doi.org/10.1038/cddis.2011.61 |