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Expression, purification, electron microscopy, N-glycosylation mutagenesis and molecular modeling of human P2X4 and Dictyostelium discoideum P2XA

The recent publication of the apo-, closed-state 3D crystal structure of zebrafish (zf) P2X4.1 has not only revolutionized the P2X research field, but also highlighted the need for further crystal structures, of receptors in different activation states, so that we can gain a complete molecular under...

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Detalles Bibliográficos
Autores principales: Valente, Maria, Watterson, Summer J., Parker, Mark D., Ford, Robert C., Young, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199733/
https://www.ncbi.nlm.nih.gov/pubmed/21889489
http://dx.doi.org/10.1016/j.bbamem.2011.08.025