Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

Neurons in the mammalian neocortex arise from asymmetric divisions of progenitors residing in the ventricular zone. While in most progenitor divisions, the mitotic spindle is parallel to the ventricular surface, some progenitors reorient the spindle and divide in oblique orientations. Here, we use c...

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Detalles Bibliográficos
Autores principales: Postiglione, Maria Pia, Jüschke, Christoph, Xie, Yunli, Haas, Gerald A., Charalambous, Christoforos, Knoblich, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199734/
https://www.ncbi.nlm.nih.gov/pubmed/22017987
http://dx.doi.org/10.1016/j.neuron.2011.09.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199734/
https://www.ncbi.nlm.nih.gov/pubmed/22017987
http://dx.doi.org/10.1016/j.neuron.2011.09.022

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