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Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway

BACKGROUND: Postconditioning (PostC) inhibits myocardial apoptosis after ischemia-reperfusion (I/R) injury. The JAK2-STAT3 pathway has anti-apoptotic effects and plays an essential role in the late protection of preconditioning. Our aim was to investigate the anti-apoptotic effect of PostC after pro...

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Detalles Bibliográficos
Autores principales: Tian, Yikui, Zhang, Wenjuan, Xia, Dachuan, Modi, Paul, Liang, Degang, Wei, Minxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199753/
https://www.ncbi.nlm.nih.gov/pubmed/21810244
http://dx.doi.org/10.1186/1423-0127-18-53