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Global transcription regulation of RK2 plasmids: a case study in the combined use of dynamical mathematical models and statistical inference for integration of experimental data and hypothesis exploration

BACKGROUND: IncP-1 plasmids are broad host range plasmids that have been found in clinical and environmental bacteria. They often carry genes for antibiotic resistance or catabolic pathways. The archetypal IncP-1 plasmid RK2 is a well-characterized biological system, with a fully sequenced and annot...

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Detalles Bibliográficos
Autores principales: Herman, Dorota, Thomas, Christopher M, Stekel, Dov J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199767/
https://www.ncbi.nlm.nih.gov/pubmed/21801369
http://dx.doi.org/10.1186/1752-0509-5-119