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Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures

BACKGROUND: Organophosphorus nerve agents irreversibly inhibit acetylcholinesterase, causing a toxic buildup of acetylcholine at muscarinic and nicotinic receptors. Current medical countermeasures to nerve agent intoxication increase survival if administered within a short period of time following e...

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Detalles Bibliográficos
Autores principales: Spradling, Kimberly D, Lumley, Lucille A, Robison, Christopher L, Meyerhoff, James L, Dillman, James F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199787/
https://www.ncbi.nlm.nih.gov/pubmed/21777429
http://dx.doi.org/10.1186/1742-2094-8-83