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Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures
BACKGROUND: Organophosphorus nerve agents irreversibly inhibit acetylcholinesterase, causing a toxic buildup of acetylcholine at muscarinic and nicotinic receptors. Current medical countermeasures to nerve agent intoxication increase survival if administered within a short period of time following e...
Autores principales: | Spradling, Kimberly D, Lumley, Lucille A, Robison, Christopher L, Meyerhoff, James L, Dillman, James F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199787/ https://www.ncbi.nlm.nih.gov/pubmed/21777429 http://dx.doi.org/10.1186/1742-2094-8-83 |
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