Cargando…

Regulation of TGF-β1-Induced Pro-Apoptotic Signaling by Growth Factor Receptors and Extracellular Matrix Receptor Integrins in the Liver

Hepatocellular carcinoma (HCC) often arises from chronically diseased livers. Persistent liver inflammation causes the accumulation of excessive extracellular matrix (ECM) proteins and impairs the liver function, finally leading to the development of HCC. A pleiotropic cytokine, transforming growth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ozaki, Iwata, Hamajima, Hiroshi, Matsuhashi, Sachiko, Mizuta, Toshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199809/ https://www.ncbi.nlm.nih.gov/pubmed/22028694 http://dx.doi.org/10.3389/fphys.2011.00078

Ejemplares similares

Regulation of interferon signaling and HCV-RNA replication by extracellular matrix
por: Kuwashiro, Takuya, et al.
Publicado: (2018)

Control Mechanisms of the Tumor Suppressor PDCD4: Expression and Functions
por: Matsuhashi, Sachiko, et al.
Publicado: (2019)

Mechanisms of PKC-Mediated Enhancement of HIF-1α Activity and its Inhibition by Vitamin K2 in Hepatocellular Carcinoma Cells
por: Xia, Jinghe, et al.
Publicado: (2019)

Activation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis
por: Svandova, Eva, et al.
Publicado: (2018)

The Calcium-Sensing Receptor and Integrins in Cellular Differentiation and Migration
por: Tharmalingam, Sujeenthar, et al.
Publicado: (2016)

Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins
por: Hudson, Shanice V., et al.
Publicado: (2017)

Anti-apoptotic and Matrix Remodeling Actions of a Small Molecule Agonist of the Human Relaxin Receptor, ML290 in Mice With Unilateral Ureteral Obstruction
por: Ng, Hooi Hooi, et al.
Publicado: (2021)

CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts
por: Man, Xiao-Yong, et al.
Publicado: (2012)

Increased (Pro)renin Receptor Expression in the Hypertensive Human Brain
por: Mohsin, Minhazul, et al.
Publicado: (2020)

Airway and Extracellular Matrix Mechanics in COPD
por: Bidan, Cécile M., et al.
Publicado: (2015)

Editorial: Physiology and Pathophysiology of the Extracellular Calcium-Sensing Receptor
por: Kallay, Enikö
Publicado: (2018)

TGF-β Signalling is Suppressed under Pro-Hypertrophic Conditions in MSC Chondrogenesis Due to TGF-β Receptor Downregulation
por: Pfeifer, Christian G., et al.
Publicado: (2019)

Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy
por: Zhang, Lin, et al.
Publicado: (2017)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Integrin β1 Promotes Pancreatic Tumor Growth by Upregulating Kindlin-2 and TGF-β Receptor-2
por: Mia, Md Saimon, et al.
Publicado: (2021)

A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8
por: Le, Viet Q., et al.
Publicado: (2023)

Integrin α2β1 Is a Receptor for the Cartilage Matrix Protein Chondroadherin
por: Camper, Lisbet, et al.
Publicado: (1997)

The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis
por: Zhou, Yingli, et al.
Publicado: (2018)

Molecular Basis of the Extracellular Ligands Mediated Signaling by the Calcium Sensing Receptor
por: Zhang, Chen, et al.
Publicado: (2016)

Inhibition of the calcium-sensing receptor by extracellular phosphate ions and by intracellular phosphorylation
por: Centeno, Patricia P., et al.
Publicado: (2023)

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation
por: Klingberg, Franco, et al.
Publicado: (2014)

Deficiency in Retinal TGFβ Signaling Aggravates Neurodegeneration by Modulating Pro-Apoptotic and MAP Kinase Pathways
por: Bielmeier, Christina B., et al.
Publicado: (2022)

Implications of TGFβ on Transcriptome and Cellular Biofunctions of Palatal Mesenchyme
por: Zhu, Xiujuan, et al.
Publicado: (2012)

Biological Significance of Local TGF-β Activation in Liver Diseases
por: Hayashi, Hiromitsu, et al.
Publicado: (2012)

Good and bad sides of TGFβ-signaling in myocardial infarction
por: Euler, Gerhild
Publicado: (2015)

TGF-β signaling in lymphatic vascular vessel formation and maintenance
por: Itoh, Fumiko, et al.
Publicado: (2022)

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis
por: d'Amaro, Rocca, et al.
Publicado: (2012)

Engineering of Human Skeletal Muscle With an Autologous Deposited Extracellular Matrix
por: Thorrez, Lieven, et al.
Publicado: (2018)

Imaging the Dynamic Interaction Between Sprouting Microvessels and the Extracellular Matrix
por: Rauff, Adam, et al.
Publicado: (2019)

Calcium-Sensing Receptor: A Key Target for Extracellular Calcium Signaling in Neurons
por: Jones, Brian L., et al.
Publicado: (2016)

Tuning properties and dynamic range of type 1 vomeronasal receptors
por: Haga-Yamanaka, Sachiko, et al.
Publicado: (2015)

Sigma-1 Receptor Activation Is Protective against TGFβ2-Induced Extracellular Matrix Changes in Human Trabecular Meshwork Cells
por: Tran, Minh Ngoc, et al.
Publicado: (2023)

TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?
por: van Caam, A., et al.
Publicado: (2020)

Thyroxine Induces Acute Relaxation of Rat Skeletal Muscle Arteries via Integrin αvβ3, ERK1/2 and Integrin-Linked Kinase
por: Selivanova, Ekaterina K., et al.
Publicado: (2021)

Progestins Inhibit Interleukin-1β-Induced Matrix Metalloproteinase 1 and Interleukin 8 Expression via the Glucocorticoid Receptor in Primary Human Amnion Mesenchymal Cells
por: Marinello, William, et al.
Publicado: (2020)

Helium ion microscopy of enamel crystallites and extracellular tooth enamel matrix
por: Bidlack, Felicitas B., et al.
Publicado: (2014)

Vesicle-Mediated Control of Cell Function: The Role of Extracellular Matrix and Microenvironment
por: Rackov, Gorjana, et al.
Publicado: (2018)

Sos1 Modulates Extracellular Matrix Synthesis, Proliferation, and Migration in Fibroblasts
por: Fuentes-Calvo, Isabel, et al.
Publicado: (2021)

Role of extracellular matrix components and structure in new renal models in vitro
por: Lacueva-Aparicio, Alodia, et al.
Publicado: (2022)

TGF-Beta Receptor II Is Critical for Osteogenic Progenitor Cell Proliferation and Differentiation During Postnatal Alveolar Bone Formation
por: Xu, Chunmei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f7c8j5s97kledfvpjulf7aco6t