Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type

BACKGROUND: Nucleolin expressed at the cell surface is a binding protein for a variety of ligands implicated in tumorigenesis and angiogenesis. By using a specific antagonist that binds the C-terminal RGG domain of nucleolin, the HB-19 pseudopeptide, we recently reported that targeting surface nucle...

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Detalles Bibliográficos
Autores principales: Krust, Bernard, El Khoury, Diala, Nondier, Isabelle, Soundaramourty, Calaiselvy, Hovanessian, Ara G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199867/
https://www.ncbi.nlm.nih.gov/pubmed/21812966
http://dx.doi.org/10.1186/1471-2407-11-333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199867/
https://www.ncbi.nlm.nih.gov/pubmed/21812966
http://dx.doi.org/10.1186/1471-2407-11-333

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