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A Bayesian Model Averaging Approach to the Quantification of Overlapping Peptides in an MALDI-TOF Mass Spectrum

In a high-resolution MALDI-TOF mass spectrum, a peptide produces multiple peaks, corresponding to the isotopic variants of the molecules. An overlap occurs when two peptides appear in the vicinity of the mass coordinate, resulting in the difficulty of quantifying the relative abundance and the exact...

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Detalles Bibliográficos
Autores principales: Zhu, Qi, Kasim, Adetayo, Valkenborg, Dirk, Burzykowski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200211/
https://www.ncbi.nlm.nih.gov/pubmed/22091391
http://dx.doi.org/10.1155/2011/928391