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Development of a Middle Cerebral Artery Occlusion Model in the Nonhuman Primate and a Safety Study of I.V. Infusion of Human Mesenchymal Stem Cells

BACKGROUND: Most experimental stroke research is carried out in rodents, but given differences between rodents and human, nonhuman primate (NHP) models may provide a valuable tool to study therapeutic interventions. The authors developed a surgical method for transient occlusion of the M1 branch of...

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Detalles Bibliográficos
Autores principales: Sasaki, Masanori, Honmou, Osamu, Radtke, Christine, Kocsis, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200343/
https://www.ncbi.nlm.nih.gov/pubmed/22039510
http://dx.doi.org/10.1371/journal.pone.0026577