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Development of a Middle Cerebral Artery Occlusion Model in the Nonhuman Primate and a Safety Study of I.V. Infusion of Human Mesenchymal Stem Cells
BACKGROUND: Most experimental stroke research is carried out in rodents, but given differences between rodents and human, nonhuman primate (NHP) models may provide a valuable tool to study therapeutic interventions. The authors developed a surgical method for transient occlusion of the M1 branch of...
Autores principales: | Sasaki, Masanori, Honmou, Osamu, Radtke, Christine, Kocsis, Jeffery D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200343/ https://www.ncbi.nlm.nih.gov/pubmed/22039510 http://dx.doi.org/10.1371/journal.pone.0026577 |
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