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Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Specific Clock Genes in the Mouse Cerebral Cortex

We have previously demonstrated that clock genes contribute to the homeostatic aspect of sleep regulation. Indeed, mutations in some clock genes modify the markers of sleep homeostasis and an increase in homeostatic sleep drive alters clock gene expression in the forebrain. Here, we investigate a po...

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Detalles Bibliográficos
Autores principales: Mongrain, Valérie, La Spada, Francesco, Curie, Thomas, Franken, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200344/
https://www.ncbi.nlm.nih.gov/pubmed/22039518
http://dx.doi.org/10.1371/journal.pone.0026622