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A Thiopurine Drug Inhibits West Nile Virus Production in Cell Culture, but Not in Mice

Many viruses within the Flavivirus genus cause significant disease in humans; however, effective antivirals against these viruses are not currently available. We have previously shown that a thiopurine drug, 6-methylmercaptopurine riboside (6MMPr), inhibits replication of distantly related viruses w...

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Detalles Bibliográficos
Autores principales: Lim, Pei-Yin, Keating, Julie A., Hoover, Spencer, Striker, Rob, Bernard, Kristen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200352/
https://www.ncbi.nlm.nih.gov/pubmed/22039536
http://dx.doi.org/10.1371/journal.pone.0026697