Cargando…
A Thiopurine Drug Inhibits West Nile Virus Production in Cell Culture, but Not in Mice
Many viruses within the Flavivirus genus cause significant disease in humans; however, effective antivirals against these viruses are not currently available. We have previously shown that a thiopurine drug, 6-methylmercaptopurine riboside (6MMPr), inhibits replication of distantly related viruses w...
Autores principales: | Lim, Pei-Yin, Keating, Julie A., Hoover, Spencer, Striker, Rob, Bernard, Kristen A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200352/ https://www.ncbi.nlm.nih.gov/pubmed/22039536 http://dx.doi.org/10.1371/journal.pone.0026697 |
Ejemplares similares
-
West Nile virus methyltransferase domain interacts with protein kinase G
por: Keating, Julie A, et al.
Publicado: (2013) -
West Nile Virus Drug Discovery
por: Lim, Siew Pheng, et al.
Publicado: (2013) -
Inhibition of West Nile Virus Multiplication in Cell Culture by Anti-Parkinsonian Drugs
por: Blázquez, Ana B., et al.
Publicado: (2016) -
Persistence of West Nile Virus in the Central Nervous System and Periphery of Mice
por: Appler, Kim K., et al.
Publicado: (2010) -
Phosphorylation events during viral infections provide potential therapeutic targets
por: Keating, Julie A., et al.
Publicado: (2012)