Alcohol Dysregulates Corticotropin-Releasing-Hormone (CRH) Promoter Activity by Interfering with the Negative Glucocorticoid Response Element (nGRE)

EtOH exposure in male rats increases corticotropin-releasing hormone (CRH) mRNA in the paraventricular nucleus of the hypothalamus (PVN), a brain region responsible for coordinating stress and anxiety responses. In this study we identified the molecular mechanisms involved in mediating these effects...

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Detalles Bibliográficos
Autores principales: Przybycien-Szymanska, Magdalena M., Mott, Natasha N., Pak, Toni R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200354/
https://www.ncbi.nlm.nih.gov/pubmed/22039522
http://dx.doi.org/10.1371/journal.pone.0026647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200354/
https://www.ncbi.nlm.nih.gov/pubmed/22039522
http://dx.doi.org/10.1371/journal.pone.0026647

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