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Reducing selection bias in case-control studies from rare disease registries

BACKGROUND: In clinical research of rare diseases, where small patient numbers and disease heterogeneity limit study design options, registries are a valuable resource for demographic and outcome information. However, in contrast to prospective, randomized clinical trials, the observational design o...

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Detalles Bibliográficos
Autores principales: Cole, J Alexander, Taylor, John S, Hangartner, Thomas N, Weinreb, Neal J, Mistry, Pramod K, Khan, Aneal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200984/
https://www.ncbi.nlm.nih.gov/pubmed/21910867
http://dx.doi.org/10.1186/1750-1172-6-61