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Reducing selection bias in case-control studies from rare disease registries
BACKGROUND: In clinical research of rare diseases, where small patient numbers and disease heterogeneity limit study design options, registries are a valuable resource for demographic and outcome information. However, in contrast to prospective, randomized clinical trials, the observational design o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200984/ https://www.ncbi.nlm.nih.gov/pubmed/21910867 http://dx.doi.org/10.1186/1750-1172-6-61 |