Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism

BACKGROUND: The development of effective drug delivery systems capable of transporting small interfering RNA (siRNA) has been elusive. We have previously reported that colorectal cancer tumor xenograft growth was arrested following treatment with liposomal preparation of siDCAMKL-1. In this report,...

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Detalles Bibliográficos
Autores principales: Sureban, Sripathi M, May, Randal, Mondalek, Fadee G, Qu, Dongfeng, Ponnurangam, Sivapriya, Pantazis, Panayotis, Anant, Shrikant, Ramanujam, Rama P, Houchen, Courtney W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200989/
https://www.ncbi.nlm.nih.gov/pubmed/21929751
http://dx.doi.org/10.1186/1477-3155-9-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200989/
https://www.ncbi.nlm.nih.gov/pubmed/21929751
http://dx.doi.org/10.1186/1477-3155-9-40

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