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Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism
BACKGROUND: The development of effective drug delivery systems capable of transporting small interfering RNA (siRNA) has been elusive. We have previously reported that colorectal cancer tumor xenograft growth was arrested following treatment with liposomal preparation of siDCAMKL-1. In this report,...
Autores principales: | Sureban, Sripathi M, May, Randal, Mondalek, Fadee G, Qu, Dongfeng, Ponnurangam, Sivapriya, Pantazis, Panayotis, Anant, Shrikant, Ramanujam, Rama P, Houchen, Courtney W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200989/ https://www.ncbi.nlm.nih.gov/pubmed/21929751 http://dx.doi.org/10.1186/1477-3155-9-40 |
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