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Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation

BACKGROUND: The yeast Saccharomyces cerevisiae responds to amino acid starvation by inducing the transcription factor Gcn4. This is mainly mediated via a translational control mechanism dependent upon the translation initiation eIF2·GTP·Met-tRNA(i)(Met )ternary complex, and the four short upstream o...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: You, Tao, Stansfield, Ian, Romano, M Carmen, Brown, Alistair JP, Coghill, George M
Μορφή: Online Άρθρο Κείμενο
Γλώσσα:English
Έκδοση: BioMed Central 2011
Θέματα:
Διαθέσιμο Online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201031/
https://www.ncbi.nlm.nih.gov/pubmed/21851603
http://dx.doi.org/10.1186/1752-0509-5-131