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Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation
BACKGROUND: The yeast Saccharomyces cerevisiae responds to amino acid starvation by inducing the transcription factor Gcn4. This is mainly mediated via a translational control mechanism dependent upon the translation initiation eIF2·GTP·Met-tRNA(i)(Met )ternary complex, and the four short upstream o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201031/ https://www.ncbi.nlm.nih.gov/pubmed/21851603 http://dx.doi.org/10.1186/1752-0509-5-131 |