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Efficient characterization of high-dimensional parameter spaces for systems biology

BACKGROUND: A biological system's robustness to mutations and its evolution are influenced by the structure of its viable space, the region of its space of biochemical parameters where it can exert its function. In systems with a large number of biochemical parameters, viable regions with poten...

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Detalles Bibliográficos
Autores principales: Zamora-Sillero, Elías, Hafner, Marc, Ibig, Ariane, Stelling, Joerg, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201035/
https://www.ncbi.nlm.nih.gov/pubmed/21920040
http://dx.doi.org/10.1186/1752-0509-5-142