Cargando…

Efficient characterization of high-dimensional parameter spaces for systems biology

BACKGROUND: A biological system's robustness to mutations and its evolution are influenced by the structure of its viable space, the region of its space of biochemical parameters where it can exert its function. In systems with a large number of biochemical parameters, viable regions with poten...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zamora-Sillero, Elías, Hafner, Marc, Ibig, Ariane, Stelling, Joerg, Wagner, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201035/ https://www.ncbi.nlm.nih.gov/pubmed/21920040 http://dx.doi.org/10.1186/1752-0509-5-142

Ejemplares similares

Topological augmentation to infer hidden processes in biological systems
por: Sunnåker, Mikael, et al.
Publicado: (2014)

A specialized ODE integrator for the efficient computation of parameter sensitivities
por: Gonnet, Pedro, et al.
Publicado: (2012)

A method for inverse bifurcation of biochemical switches: inferring parameters from dose response curves
por: Otero-Muras, Irene, et al.
Publicado: (2014)

Robust and efficient parameter estimation in dynamic models of biological systems
por: Gábor, Attila, et al.
Publicado: (2015)

Penalized Ordinal Regression Methods for Predicting Stage of Cancer in High-Dimensional Covariate Spaces
por: Gentry, Amanda Elswick, et al.
Publicado: (2015)

Combining acoustic tracking and LiDAR to study bat flight behaviour in three-dimensional space
por: Hermans, Claire, et al.
Publicado: (2023)

Computational analysis of viable parameter regions in models of synthetic biological systems
por: Pušnik, žiga, et al.
Publicado: (2019)

Efficient randomization of biological networks while preserving functional characterization of individual nodes
por: Iorio, Francesco, et al.
Publicado: (2016)

Identification of parameter correlations for parameter estimation in dynamic biological models
por: Li, Pu, et al.
Publicado: (2013)

A straightforward and efficient analytical pipeline for metaproteome characterization
por: Tanca, Alessandro, et al.
Publicado: (2014)

An accurate and efficient experimental approach for characterization of the complex oral microbiota
por: Zheng, Wei, et al.
Publicado: (2015)

Robust differential expression analysis by learning discriminant boundary in multi-dimensional space of statistical attributes
por: Bei, Yuanzhe, et al.
Publicado: (2016)

A robust protocol for efficient generation, and genomic characterization of insertional mutants of Chlamydomonas reinhardtii
por: Pollock, Steve V., et al.
Publicado: (2017)

High-efficiency procedure to characterize, segment, and quantify complex multicellularity in raw micrographs in plants
por: Zhang, Xi, et al.
Publicado: (2020)

Efficient classification of complete parameter regions based on semidefinite programming
por: Kuepfer, Lars, et al.
Publicado: (2007)

Visualizing histopathologic deep learning classification and anomaly detection using nonlinear feature space dimensionality reduction
por: Faust, Kevin, et al.
Publicado: (2018)

Parameter estimation in systems biology models using spline approximation
por: Zhan, Choujun, et al.
Publicado: (2011)

Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
por: Rodriguez-Fernandez, Maria, et al.
Publicado: (2006)

Parameter identifiability-based optimal observation remedy for biological networks
por: Wang, Yulin, et al.
Publicado: (2017)

Exercise in space: the European Space Agency approach to in-flight exercise countermeasures for long-duration missions on ISS
por: Petersen, Nora, et al.
Publicado: (2016)

Characterization of the Effectiveness of Reporting Lists of Small Feature Sets Relative to the Accuracy of the Prior Biological Knowledge
por: Zhao, Chen, et al.
Publicado: (2010)

Mapping behavioral specifications to model parameters in synthetic biology
por: Koeppl, Heinz, et al.
Publicado: (2013)

Correlation analysis of two-dimensional gel electrophoretic protein patterns and biological variables
por: Van Belle, Werner, et al.
Publicado: (2006)

Biological sequences as pictures – a generic two dimensional solution for iterated maps
por: Almeida, Jonas S, et al.
Publicado: (2009)

Optimal experiment selection for parameter estimation in biological differential equation models
por: Transtrum, Mark K, et al.
Publicado: (2012)

Parameter estimation of dynamic biological network models using integrated fluxes
por: Liu, Yang, et al.
Publicado: (2014)

Parameter estimation in models of biological oscillators: an automated regularised estimation approach
por: Pitt, Jake Alan, et al.
Publicado: (2019)

Motif mining based on network space compression
por: Zhang, Qiang, et al.
Publicado: (2014)

Efficient multiplex mutagenesis by RNA-guided Cas9 and its use in the characterization of regulatory elements in the AGAMOUS gene
por: Yan, Wenhao, et al.
Publicado: (2016)

A novel applicability domain technique for mapping predictive reliability across the chemical space of a QSAR: reliability-density neighbourhood
por: Aniceto, Natália, et al.
Publicado: (2016)

An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum
por: Wagner, Jeffrey C, et al.
Publicado: (2013)

Nested sampling for parameter inference in systems biology: application to an exemplar circadian model
por: Aitken, Stuart, et al.
Publicado: (2013)

A cooperative strategy for parameter estimation in large scale systems biology models
por: Villaverde, Alejandro F, et al.
Publicado: (2012)

Three-dimensional foot shape analysis in children: a pilot analysis using three-dimensional shape descriptors
por: Varga, Matyas, et al.
Publicado: (2020)

Differentiating anomalous disease intensity with confounding variables in space
por: Wu, Chih-Chieh, et al.
Publicado: (2020)

A high-throughput sequencing assay to comprehensively detect and characterize unicellular eukaryotes and helminths from biological and environmental samples
por: Cannon, Matthew V., et al.
Publicado: (2018)

An efficiency analysis of high-order combinations of gene–gene interactions using multifactor-dimensionality reduction
por: Yang, Cheng-Hong, et al.
Publicado: (2015)

Development and validation of a clinical tool to semi-automatic measure three-dimensional TAR alignment on two-dimensional radiographs
por: van Hoogstraten, Sanne W. G., et al.
Publicado: (2023)

Hamiltonian Monte Carlo methods for efficient parameter estimation in steady state dynamical systems
por: Kramer, Andrei, et al.
Publicado: (2014)

Root Hair Sizer: an algorithm for high throughput recovery of different root hair and root developmental parameters
por: Guichard, Marjorie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_67ho52umscjvpetkkibliadqla