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Cyclization of 5-hexynoic acid to 3-alkoxy-2-cyclohexenones

The one-pot cyclization of 5-hexynoic acid to produce 3-alkoxy-2-cyclohexenones proceeds in good yields (58–90%). 3-Hexynoic acid was converted to its acyl chloride with the aid of oxalyl chloride and was cyclized to 3-chloro-2-cyclohexenone upon addition of indium(III) chloride. Subsequent addition...

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Detalles Bibliográficos
Autores principales:	Hylden, Anne T, Uzelac, Eric J, Ostojic, Zeljko, Wu, Ting-Ting, Sacry, Keely L, Sacry, Krista L, Xi, Lin, Jones, T Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2011
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201045/ https://www.ncbi.nlm.nih.gov/pubmed/22043242 http://dx.doi.org/10.3762/bjoc.7.155

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