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In Vitro Enhanced Sensitivity to Cisplatin in D67Y BRCA1 RING Domain Protein

BRCA1 is a tumor suppressor protein involved in maintaining genomic integrity through multiple functions in DNA damage repair, transcriptional regulation, cell cycle checkpoint, and protein ubiquitination. The BRCA1-BARD1 RING complex has an E3 ubiquitin ligase function that plays essential roles in...

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Detalles Bibliográficos
Autores principales: Atipairin, Apichart, Ratanaphan, Adisorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201098/
https://www.ncbi.nlm.nih.gov/pubmed/22084573
http://dx.doi.org/10.4137/BCBCR.S8184