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Antitumor Efficacy of Intravesical BCG, Gemcitabine, Interferon-α and Interleukin-2 as Mono- or Combination-Therapy for Bladder Cancer in an Orthotopic Tumor Model

OBJECTIVE: To reduce adverse effects and improve efficacy of intravesical BCG for bladder cancer, alternative treatment options were investigated in an orthotopic rat tumor model. METHODS: Superficial bladder cancer was established in syngeneic female rat bladders by instillation of AY-27 cells. Ani...

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Detalles Bibliográficos
Autores principales: Xiao, Zhengwen, Hanel, Erich, Mak, Allan, Moore, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201113/
https://www.ncbi.nlm.nih.gov/pubmed/22084620
http://dx.doi.org/10.4137/CMO.S7658