Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

Pluripotency is a developmental ground state that can be recreated by direct reprogramming. Establishment of pluripotency is crucially dependent on the homeodomain-containing transcription factor Nanog. Compared with other pluripotency-associated genes, however, Nanog shows relatively low sequence c...

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Detalles Bibliográficos
Autores principales: Theunissen, Thorold W., Costa, Yael, Radzisheuskaya, Aliaksandra, van Oosten, Anouk L., Lavial, Fabrice, Pain, Bertrand, Castro, L. Filipe C., Silva, José C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2011
Materias:
Development and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201656/
https://www.ncbi.nlm.nih.gov/pubmed/22028025
http://dx.doi.org/10.1242/dev.068775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201656/
https://www.ncbi.nlm.nih.gov/pubmed/22028025
http://dx.doi.org/10.1242/dev.068775

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