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Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection

Understanding the nature of the free state of riboswitch aptamers is important for illuminating common themes in gene regulation by riboswitches. Prior evidence indicated the flavin mononucleotide (FMN)-binding riboswitch aptamer adopted a ‘bound-like’ structure in absence of FMN, suggesting only lo...

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Detalles Bibliográficos
Autores principales: Vicens, Quentin, Mondragón, Estefanía, Batey, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201879/
https://www.ncbi.nlm.nih.gov/pubmed/21745821
http://dx.doi.org/10.1093/nar/gkr565