Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs

BACKGROUND: Eggs deposited in the liver of the mammalian host by the blood fluke parasite, Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response in immune-competent mice. By contrast, in mice deprived of T-cells and incapable of producing granulomata, egg-secreted pr...

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Detalles Bibliográficos
Autores principales: Abdulla, Maha-Hamadien, Lim, Kee-Chong, McKerrow, James H., Caffrey, Conor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201919/
https://www.ncbi.nlm.nih.gov/pubmed/22039561
http://dx.doi.org/10.1371/journal.pntd.0001368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201919/
https://www.ncbi.nlm.nih.gov/pubmed/22039561
http://dx.doi.org/10.1371/journal.pntd.0001368

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