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Methadone adverse reaction presenting with large increase in plasma methadone binding: a case series

INTRODUCTION: The use of methadone as an analgesic is on the increase, but it is widely recognized that the goal of predictable and reproducible dosing is confounded by considerable variability in methadone pharmacokinetics, and unpredictable side effects that include sedation, respiratory depressio...

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Detalles Bibliográficos
Autores principales: Lu, Wenjie J, Zhou, Weidong, Kreutz, Yvonne, Flockhart, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201932/
https://www.ncbi.nlm.nih.gov/pubmed/21985665
http://dx.doi.org/10.1186/1752-1947-5-513