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Methadone adverse reaction presenting with large increase in plasma methadone binding: a case series
INTRODUCTION: The use of methadone as an analgesic is on the increase, but it is widely recognized that the goal of predictable and reproducible dosing is confounded by considerable variability in methadone pharmacokinetics, and unpredictable side effects that include sedation, respiratory depressio...
Autores principales: | Lu, Wenjie J, Zhou, Weidong, Kreutz, Yvonne, Flockhart, David A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201932/ https://www.ncbi.nlm.nih.gov/pubmed/21985665 http://dx.doi.org/10.1186/1752-1947-5-513 |
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