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Carbon Monoxide Induced PPARγ SUMOylation and UCP2 Block Inflammatory Gene Expression in Macrophages

Carbon monoxide (CO) dampens pro-inflammatory responses in a peroxisome proliferator-activated receptor-γ (PPARγ) and p38 mitogen-activated protein kinase (MAPK) dependent manner. Previously, we demonstrated that CO inhibits lipopolysaccharide (LPS)-induced expression of the proinflammatory early gr...

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Detalles Bibliográficos
Autores principales: Haschemi, Arvand, Chin, Beek Yoke, Jeitler, Markus, Esterbauer, Harald, Wagner, Oswald, Bilban, Martin, Otterbein, Leo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201958/
https://www.ncbi.nlm.nih.gov/pubmed/22046279
http://dx.doi.org/10.1371/journal.pone.0026376