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EP Receptor Expression in Human Intestinal Epithelium and Localization Relative to the Stem Cell Zone of the Crypts

There is substantial evidence for PGE2 affecting intestinal epithelial proliferation. PGE2 is also reported to be involved in the regulation of growth and differentiation in adult stem cells, both effects mediated by binding to EP-receptors. We have used the Lgr5 as a marker to scrutinize EP-recepto...

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Detalles Bibliográficos
Autores principales: Olsen Hult, Lene Th., Kleiveland, Charlotte R., Fosnes, Kjetil, Jacobsen, Morten, Lea, Tor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201980/
https://www.ncbi.nlm.nih.gov/pubmed/22046368
http://dx.doi.org/10.1371/journal.pone.0026816