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The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors

Although the physiological function of the cellular prion protein (PrP(C)) remains unknown, several evidences support the notion of its role in copper homeostasis. PrP(C) binds Cu(2+) through a domain composed by four to five repeats of eight amino acids. Previously, we have shown that the perfusion...

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Detalles Bibliográficos
Autores principales: Lorca, Ramón A., Varela-Nallar, Lorena, Inestrosa, Nibaldo C., Huidobro-Toro, J. Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202100/
https://www.ncbi.nlm.nih.gov/pubmed/22114745
http://dx.doi.org/10.4061/2011/706576