Alcohol Activates TGF-Beta but Inhibits BMP Receptor-Mediated Smad Signaling and Smad4 Binding to Hepcidin Promoter in the Liver

Hepcidin, a key regulator of iron metabolism, is activated by bone morphogenetic proteins (BMPs). Mice pair-fed with regular and ethanol-containing L. De Carli diets were employed to study the effect of alcohol on BMP signaling and hepcidin transcription in the liver. Alcohol induced steatosis and T...

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Detalles Bibliográficos
Autores principales: Gerjevic, Lisa Nicole, Liu, Na, Lu, Sizhao, Harrison-Findik, Duygu Dee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202137/
https://www.ncbi.nlm.nih.gov/pubmed/22121494
http://dx.doi.org/10.1155/2012/459278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202137/
https://www.ncbi.nlm.nih.gov/pubmed/22121494
http://dx.doi.org/10.1155/2012/459278

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