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Cervicovaginal Safety of the Formulated, Biguanide-Based Human Immunodeficiency Virus Type 1 (HIV-1) Inhibitor NB325 in a Murine Model

Vaginal microbicides that reduce or eliminate the risk of HIV-1 sexual transmission must do so safely without adversely affecting the integrity of the cervicovaginal epithelium. The present studies were performed to assess the safety of the biguanide-based antiviral compound NB325 in a formulation s...

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Detalles Bibliográficos
Autores principales: Lozenski, Karissa, Kish-Catalone, Tina, Pirrone, Vanessa, Rando, Robert F., Labib, Mohamed, Wigdahl, Brian, Krebs, Fred C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202145/
https://www.ncbi.nlm.nih.gov/pubmed/22131821
http://dx.doi.org/10.1155/2011/941061