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Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

BACKGROUND: Neuro-glial interactions are important for normal functioning of the brain as well as brain energy metabolism. There are two major working models - in the classical view, both neurons and astrocytes can utilize glucose as the energy source through oxidative metabolism, whereas in the ast...

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Detalles Bibliográficos
Autores principales: Genc, Seda, Kurnaz, Isil A, Ozilgen, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202240/
https://www.ncbi.nlm.nih.gov/pubmed/21995951
http://dx.doi.org/10.1186/1752-0509-5-162