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Altered Expression of Insulin Receptor Isoforms in Breast Cancer

PURPOSE: Insulin-like growth factor (IGF) signaling through human insulin receptor isoform A (IR-A) contributes to tumorigenesis and intrinsic resistance to anti-IGF1R therapy. In the present study, we (a) developed quantitative TaqMan real time-PCR-based assays (qRT-PCR) to measure human insulin re...

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Detalles Bibliográficos
Autores principales: Huang, Jiaqi, Morehouse, Chris, Streicher, Katie, Higgs, Brandon W., Gao, Jin, Czapiga, Meggan, Boutrin, Anmarie, Zhu, Wei, Brohawn, Philip, Chang, Yong, Viner, Jaye, LaVallee, Theresa, Richman, Laura, Jallal, Bahija, Yao, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202518/
https://www.ncbi.nlm.nih.gov/pubmed/22046260
http://dx.doi.org/10.1371/journal.pone.0026177