Bovine Herpesvirus Type 1 (BHV-1) U(L)49.5 Luminal Domain Residues 30 to 32 Are Critical for MHC-I Down-Regulation in Virus-Infected Cells

Bovine herpesvirus type 1 (BHV-1) U(L)49.5 inhibits transporter associated with antigen processing (TAP) and down-regulates cell-surface expression of major histocompatibility complex (MHC) class I molecules to promote immune evasion. We have constructed a BHV-1 U(L)49.5 cytoplasmic tail (CT) null a...

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Detalles Bibliográficos
Autores principales: Wei, Huiyong, Wang, Ying, Chowdhury, Shafiqul I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202525/
https://www.ncbi.nlm.nih.gov/pubmed/22046246
http://dx.doi.org/10.1371/journal.pone.0025742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202525/
https://www.ncbi.nlm.nih.gov/pubmed/22046246
http://dx.doi.org/10.1371/journal.pone.0025742

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