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Effect of DNA Groove Binder Distamycin A upon Chromatin Structure
BACKGROUND: Distamycin A is a prototype minor groove binder, which binds to B-form DNA, preferentially at A/T rich sites. Extensive work in the past few decades has characterized the binding at the level of double stranded DNA. However, effect of the same on physiological DNA, i.e. DNA complexed in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202541/ https://www.ncbi.nlm.nih.gov/pubmed/22046291 http://dx.doi.org/10.1371/journal.pone.0026486 |