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Effect of DNA Groove Binder Distamycin A upon Chromatin Structure

BACKGROUND: Distamycin A is a prototype minor groove binder, which binds to B-form DNA, preferentially at A/T rich sites. Extensive work in the past few decades has characterized the binding at the level of double stranded DNA. However, effect of the same on physiological DNA, i.e. DNA complexed in...

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Detalles Bibliográficos
Autores principales: Majumder, Parijat, Dasgupta, Dipak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202541/
https://www.ncbi.nlm.nih.gov/pubmed/22046291
http://dx.doi.org/10.1371/journal.pone.0026486