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The CDKN2A G500 Allele Is More Frequent in GBM Patients with No Defined Telomere Maintenance Mechanism Tumors and Is Associated with Poorer Survival

Prognostic markers for glioblastoma multiforme (GBM) are important for patient management. Recent advances have identified prognostic markers for GBMs that use telomerase or the alternative lengthening of telomeres (ALT) mechanism for telomere maintenance. Approximately 40% of GBMs have no defined t...

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Detalles Bibliográficos
Autores principales: Royds, Janice A., Al Nadaf, Shafagh, Wiles, Anna K., Chen, Yu-Jen, Ahn, Antonio, Shaw, Alisha, Bowie, Sara, Lam, Frederic, Baguley, Bruce C., Braithwaite, Antony W., MacFarlane, Martin R., Hung, Noelyn A., Slatter, Tania L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202568/
https://www.ncbi.nlm.nih.gov/pubmed/22046342
http://dx.doi.org/10.1371/journal.pone.0026737